5.1 Protein-Protein Interactions

Depending on their functions, proteins have a very wide range of affinities. Typical K_d values range from 10^-12 to 10^-6 M.⁴

The general features in protein-protein interactions are the same as those in protein folding!

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4. This range corresponds to binding free energies of about -70 kJ / mol to -35 kJ / mol at 37\(^\omicron\)C↩︎