8 Overview

The connecting module is one of the key components of the myCMIE app. It provides several functions allowing users to look for similar tumor profiles in the public domain based on the patient’s total profile. We want to provide more insights into the patient’s genomic data based on public data but related to sample data at a larger scale.

8.1 Start connecting

We provide functions for profile matching using TCGA samples and CCLE (Ghandi2019?)cell lines.

8.2 Community pool

Users are allowed to choose a query pool from:

  • TCGA: 30 cancer types, 10,967 samples in total.

  • CCLE: 30 cancer types, 1,739 cell lines in total.

  • Users-define: Users are allowed to upload their own data from their cancer center as a query pool. (see 11 MatchMore chapter )

Also, we provide a function allowing users to filter a subset of samples by the clinical features of the querying patient case, with the purpose of getting more clinically related sample matching.

Below is an example:

The results here are in whole or part based upon data generated by the TCGA Research Network: https://www.cancer.gov/tcga.