10.1 Supplemental tables | MODELS TO INFORM THE SAFE COLLECTION AND TRANSFUSION OF DONATED BLOOD

Table 10.1: List of features for prediction model with description and notes from feature engineering.
Variable name	Description	Feature engineering
Donation history
DER_RBC_Last12months	Red blood cell loss in last 12 months	Used as-is.
DER_RBC_Last24months	Red blood cell loss in last 24 months	Used as-is.
DER_RBCLoss_Units	Units of red blood cell lost at this donation	Used as-is.
DER_RBCLoss_mL	Volume of red blood cell loss at this donation (mL)	Used as-is.
DER_DaysRBCLoss	Days since last red blood cell loss	Set NAs (36%) to 10 years ago (10*365 days)
DER_DaysDRLoss	Days since last double red blood cell donation	Set NAs (36%) to 10 years ago (10*365 days)
RQ1_Ever_Donated	Ever donated blood before	Recoded to 0 (no), 1 (yes); set as 1 for all followup donations since they gave an index donation
cumLifetimeDonations	Total lifetime donations	If lifetime donations missing from baseline questionaire, set to 0. For follow-up visits, increased by 1 for all donations.
Biometric
FingerstickHGB_equiv	Fingerstick HGB or HCT	Used fingerstick HGB if measured. Otherwise, used fingerstick HCT/3.04. If also missing, used adjusted venous HGB.
DD_ABO_RH	ABO-Rh blood type	1 donor has UNT. Setting to most common value in dataset, O+ (40% of donors at baseline)
DER_AdjVenousHgb	Venous HGB (converted to pre-donation if measured from a post-donation sample)	Not collected at all follow-up visits. If missing, set to fingerstick value
DER_Weight	Weight (pounds)	Missing for 5 donors with 22 follow-up donations. 4 M, 1 F, ages 27 - 69. Imputing mean weight by gender among those aged >25
DER_Height	Height (inches)	Missing for 6 donors (same 5 missing weight plus one additional) with 23 follow-up donations. Age 27 - 69. Imputing mean height by gender amon those age >25.
BMI	Body Mass Index	Missing for same 6 donors missing height. Calculating from (imputed) weight and height
DER_EBV	Estimated Blood Volume (Nadler's equations)	None missing
DER_RedCellVolume	Total body red blood cell volume	Calculated total body red cell volume; none missing
DER_PercentRBCLoss	Estimated percent red blood cell volume loss at visit	Percent of red cell lost at donation; none missing
DER_Age	Age	Available for all, 18 - 87
Survey responses from baseline visit
DD_Country	US born	1 if US-born, 0 otherwise. Missing for <1%; if missing re-coding as US-born (>95%)
DD_Gender	Gender	no missing. 52% female at baseline; 51% for followups
DD_Raceth	Race/ethnicity (Asian, Black, Hispanic, Other, White)	0.7% missing; Recoding to "O" (other)
RQ7_Ever_Smoked	Smoked at least 100 cigarettes in lifetime	Recoding to 0 (no) and 1(yes). For "don't know" (26) and "missing" (10), coding to "no" because majority (60%)
RQ8_Smoked_Past_90Days	Smoked in last 90 days	Recoding to 0 no and 1 yes. If NA (60%) or don't know (3%), recoding to no (68% of respondents)
RQ11_Liver	Liver consumption (times per week)	Recoding as times per week 0 (never), 0.5 (<1/wk), 1 (1/wk), 2 (2/wk), 3.5 (3-4x/wk), 5.5 (5-6x/wk), 7 (daily), 14 (2x or more/day); 59 are 99 (blank/don't know); setting them to most common which was never
RQ11_Beef	Beef consumption (times per week)	Recoding as times per week 0 (never), 0.5 (<1/wk), 1 (1/wk), 2 (2/wk), 3.5 (3-4x/wk), 5.5 (5-6x/wk), 7 (daily), 14 (2x or more/day); 98 are 99 (blank/don't know); setting them to most common which was 2x/wk
RQ11_LPCT	Lamb, pork, chicken, or turkey consumption (times per week)	Recoding as times per week 0 (never), 0.5 (<1/wk), 1 (1/wk), 2 (2/wk), 3.5 (3-4x/wk), 5.5 (5-6x/wk), 7 (daily), 14 (2x or more/day); 59 are 99 (blank/don't know); setting them to most common which was 3.5x/wk
RQ11_Clams	Clams consumption (times per week)	Recoding as times per week 0 (never), 0.5 (<1/wk), 1 (1/wk), 2 (2/wk), 3.5 (3-4x/wk), 5.5 (5-6x/wk), 7 (daily), 14 (2x or more/day); 121 are 99 (blank/don't know); setting them to most common which was never
RQ11_OMSS	Oysters, mussels, shrimp, or sardines consumption (times per week)	Oysters, mussels, shrimp, sardines. Recoding as times per week 0 (never), 0.5 (<1/wk), 1 (1/wk), 2 (2/wk), 3.5 (3-4x/wk), 5.5 (5-6x/wk), 7 (daily), 14 (2x or more/day); 100 are 99 (blank/don't know); setting them to most common which was less than 1/wk
RQ11_OtrFish	Other fish consumption (times per week)	Recoding as times per week 0 (never), 0.5 (<1/wk), 1 (1/wk), 2 (2/wk), 3.5 (3-4x/wk), 5.5 (5-6x/wk), 7 (daily), 14 (2x or more/day); 38 are 99 (blank/don't know); setting them to most common which was <1x/wk
RQ11_Eggs	Egg consumption (times per week)	Recoding as times per week 0 (never), 0.5 (<1/wk), 1 (1/wk), 2 (2/wk), 3.5 (3-4x/wk), 5.5 (5-6x/wk), 7 (daily), 14 (2x or more/day); 62 are 99 (blank/don't know); setting them to most common which was 1x/wk
RQ11_Dairy	Dairy consumption (times per week)	Recoding as times per week 0 (never), 0.5 (<1/wk), 1 (1/wk), 2 (2/wk), 3.5 (3-4x/wk), 5.5 (5-6x/wk), 7 (daily), 14 (2x or more/day); 33 are 99 (blank/don't know); setting them to most common which was 1x/day
compositeIronScore	Composite dietary iron score	Missing for 13 at baseline. Imputing mean.
supp_iron_pct_of_daily	Supplemental iron	Value between 0 (no iron suppl) and 1 (daily iron suppl), where multivitamins or iron supplementation are both counted as supplemental iron. Computed as min(1, (ironsupp_per_week+RQ12C_MV_WithIron_YN*multivitamins_per_week)/7))
multivitamins_per_week	Multivitimin consumption (times per week)	Based on RQ12A_MultiVitamins_YN and RQ12B_MultiVitamins_How_Often. Recoding to times per week. "1: everyday" becomes 7; "2: 4-6x per week" becomes 5; "3: 1-3 days per week" becomes 2. Don't know/missing (51) set to daily (7/wk). If they answered yes to taking multivitamins but missing or don't know for how often, coding as 4-6x per week.
RQ17_NumberOfPeriods	Periods in last year	Original is NA for all men and all women who say their period stopped, and for one F 19yo donor who answered NA to menstrual status question, likely because she is pre-menstrual and that wasn't an option. Coding all NAs as 0. Also, equal to 99 (don't know) for 13 donors who said yes to having periods. Coding to the most common value which is 12.
RQ18_Menstrual_Flow	Menstrual flow intensity	Recoding as 0 for no period, 1 for spotting, 2 for very light, 3 for light, 4 for moderate, 5 for heavy, 6 for very heavy/gushing. 3 women who have periods had a '9', presumably don't know or refused to answer. Recoding to most common answer, which was 4 (moderate),
menstrual_flow_times_freq	Menstrual frequency and flow	RQ19_MenstrualFlow/5 * RQ17_NumberOf_Periods/12
RQ19_Ever_Pregnant	Ever pregnant	Originally NA for all men and 10 women. Recoding as 0 (no) and 1 (yes), all NAs coded as 0.
RQ20_NumberOfPregnancies	Number of pregnancies	Originally NA for all men and 356 women (same as never pregnant), 1-6 for other women. Coding NAs as 0.
RQ21_NumberOfLiveBirths	Number of live births	Originally NA fo rall men and 356 women; Coding NAs as 0.
gender_menstrating_cohorts	Gender & menstration cohort	3 categories: male, female menstrating (>0 periods in last year), female not menstrating (0 periods in last year)
Additional biometrics available for some donations
ARUP_Ferritin	Ferritin (mg/dL)	Use as-is for secondary analysis.
ARUP_STR	Soluble Transferrin Receptor (STfR) (nmol/L)	Use as-is for secondary analysis.
DER_ARUP_log_Ferr	Log of ferritin	Use as-is for secondary analysis.
DER_ARUP_log_STfR_Ferr	STfR divided by the log of ferritin	Use as-is for secondary analysis.
DER_BodyIron	Body iron in mg/kg calculated from STfR	Use as-is for secondary analysis.

Table 10.2: Model types and hyperparameters assessed as candidates. All hyperparameter combinations were assessed in 5-fold cross validation on each of 15 model validation sets defined by the nested cross validation scheme.
Hyperparameters	Values assessed	Top configuration hyperparameter value	Top configuration AUC (mean and range)
Gradient boosted decision trees (R package xgboost)
Learning rate	0.01, 0.05, 0.1, 0.3	0.01	75.4% (75.1 to 75.8)
Maximum tree depth	2, 4, 6, 8, 10, 12, 14, 16, 18, 20	18
Minimum child weight	0, 1, 2, 4, 8	1
Row subsampling per tree	0.65, 0.8, 1	0.65
column subsampling per tree	0.8, 0.9, 1	0.8
Random forest (R package randomForest)
Minimum size of terminal nodes	1, 2, 4, 8	4	75.2% (74.7 to 75.7)
Maximum number of trees	250, 500, 750, 1000, 1250, 1500, 1750, 2000, 2250, 2500	1500
Sampling with replacement?	yes, no	yes
Elasticnet penalized logistic regression (R package glmnet)
alpha (0 = ridge, 1 = lasso)	0, .25, .5, .75, 1	NA	72.5% (72.1 to 72.8)
lambda (penalty weight)	0, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1	0
Elasticnet with all second order interactions (R package glmnet)
alpha (0 = ridge, 1 = lasso)	0, .25, .5, .75, 1	0	73.8% (73.3 to 74.1)
lambda (penalty weight)	0, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1	0.05
Regression trees (R package rpart)
Complexity parameter	0.001, 0.005, 0.01, 0.05, 0.1	0.005	66.4% (65.8 to 67.0)
Minimum observations per split	10, 15, 20, 25, 30	20

Table 10.3: Estimated collections and adverse events per 100 donor years.
Policy	Collections	Hemoglobin deferrals	Low iron donations	Absent iron donations
Uniform interval policies1
status quo 56W-56M	408	43.6	126	96
Can 84W-56M	373	31.8	114	79
Aus 84W-84M	325	25.6	87	67
UK 112W-84M	293	18.5	73	54
Tailored policies2
Tailored 0.1H-0.1L-0.1A	198	5.8	33	18
Tailored 0.2H-0.1L-0.1A	199	6.3	33	18
Tailored 0.3H-0.1L-0.1A	199	6.4	33	18
Tailored 0.4H-0.1L-0.1A	199	6.6	33	18
Tailored 0.5H-0.1L-0.1A	199	6.6	33	18
Tailored 0.6H-0.1L-0.1A	199	6.7	33	18
Tailored 0.7H-0.1L-0.1A	199	6.8	33	18
Tailored 0.8H-0.1L-0.1A	199	6.9	33	18
Tailored 0.9H-0.1L-0.1A	199	7.1	33	18
Tailored 0.1H-0.2L-0.1A	257	8.8	58	26
Tailored 0.2H-0.2L-0.1A	258	9.8	58	26
Tailored 0.3H-0.2L-0.1A	258	10.2	59	26
Tailored 0.4H-0.2L-0.1A	259	10.6	59	26
Tailored 0.5H-0.2L-0.1A	259	10.7	59	26
Tailored 0.6H-0.2L-0.1A	259	10.8	59	26
Tailored 0.7H-0.2L-0.1A	259	10.9	59	26
Tailored 0.8H-0.2L-0.1A	259	11.0	59	26
Tailored 0.9H-0.2L-0.1A	259	11.2	59	26
Tailored 0.1H-0.3L-0.1A	281	9.9	74	29
Tailored 0.2H-0.3L-0.1A	283	11.3	75	30
Tailored 0.3H-0.3L-0.1A	284	12.0	75	30
Tailored 0.4H-0.3L-0.1A	284	12.3	75	30
Tailored 0.5H-0.3L-0.1A	284	12.5	75	30
Tailored 0.6H-0.3L-0.1A	284	12.6	75	30
Tailored 0.7H-0.3L-0.1A	284	12.7	75	30
Tailored 0.8H-0.3L-0.1A	284	12.8	75	30
Tailored 0.9H-0.3L-0.1A	284	13.0	75	30
Tailored 0.1H-0.4L-0.1A	292	10.4	82	31
Tailored 0.2H-0.4L-0.1A	294	12.0	83	31
Tailored 0.3H-0.4L-0.1A	295	12.7	83	31
Tailored 0.4H-0.4L-0.1A	295	13.1	84	31
Tailored 0.5H-0.4L-0.1A	295	13.3	84	31
Tailored 0.6H-0.4L-0.1A	295	13.4	84	31
Tailored 0.7H-0.4L-0.1A	295	13.5	84	31
Tailored 0.8H-0.4L-0.1A	295	13.6	84	31
Tailored 0.9H-0.4L-0.1A	295	13.8	84	31
Tailored 0.1H-0.5L-0.1A	296	10.6	86	31
Tailored 0.2H-0.5L-0.1A	299	12.2	87	32
Tailored 0.3H-0.5L-0.1A	300	12.9	88	32
Tailored 0.4H-0.5L-0.1A	300	13.4	88	32
Tailored 0.5H-0.5L-0.1A	300	13.6	88	32
Tailored 0.6H-0.5L-0.1A	300	13.7	88	32
Tailored 0.7H-0.5L-0.1A	300	13.7	88	32
Tailored 0.8H-0.5L-0.1A	300	13.8	88	32
Tailored 0.9H-0.5L-0.1A	300	14.0	88	32
Tailored 0.1H-0.6L-0.1A	298	10.7	87	32
Tailored 0.2H-0.6L-0.1A	301	12.3	89	32
Tailored 0.3H-0.6L-0.1A	302	13.0	89	32
Tailored 0.4H-0.6L-0.1A	302	13.5	89	32
Tailored 0.5H-0.6L-0.1A	302	13.7	89	32
Tailored 0.6H-0.6L-0.1A	302	13.8	89	32
Tailored 0.7H-0.6L-0.1A	302	13.9	89	32
Tailored 0.8H-0.6L-0.1A	302	14.0	89	32
Tailored 0.9H-0.6L-0.1A	302	14.2	89	32
Tailored 0.1H-0.7L-0.1A	299	10.7	88	32
Tailored 0.2H-0.7L-0.1A	302	12.4	89	32
Tailored 0.3H-0.7L-0.1A	302	13.1	90	32
Tailored 0.4H-0.7L-0.1A	302	13.5	90	32
Tailored 0.5H-0.7L-0.1A	303	13.7	90	32
Tailored 0.6H-0.7L-0.1A	303	13.8	90	32
Tailored 0.7H-0.7L-0.1A	303	13.9	90	32
Tailored 0.8H-0.7L-0.1A	303	14.0	90	32
Tailored 0.9H-0.7L-0.1A	303	14.2	90	32
Tailored 0.1H-0.8L-0.1A	299	10.7	88	32
Tailored 0.2H-0.8L-0.1A	302	12.4	89	32
Tailored 0.3H-0.8L-0.1A	302	13.1	90	32
Tailored 0.4H-0.8L-0.1A	303	13.5	90	32
Tailored 0.5H-0.8L-0.1A	303	13.7	90	32
Tailored 0.6H-0.8L-0.1A	303	13.8	90	32
Tailored 0.7H-0.8L-0.1A	303	13.9	90	32
Tailored 0.8H-0.8L-0.1A	303	14.0	90	32
Tailored 0.9H-0.8L-0.1A	303	14.2	90	32
Tailored 0.1H-0.9L-0.1A	299	10.7	88	32
Tailored 0.2H-0.9L-0.1A	302	12.4	89	32
Tailored 0.3H-0.9L-0.1A	302	13.1	90	32
Tailored 0.4H-0.9L-0.1A	303	13.5	90	32
Tailored 0.5H-0.9L-0.1A	303	13.7	90	32
Tailored 0.6H-0.9L-0.1A	303	13.8	90	32
Tailored 0.7H-0.9L-0.1A	303	13.9	90	32
Tailored 0.8H-0.9L-0.1A	303	14.0	90	32
Tailored 0.9H-0.9L-0.1A	303	14.2	90	32
Tailored 0.1H-0.2L-0.2A	275	11.0	63	34
Tailored 0.2H-0.2L-0.2A	277	13.2	64	35
Tailored 0.3H-0.2L-0.2A	278	14.1	64	35
Tailored 0.4H-0.2L-0.2A	278	14.7	65	35
Tailored 0.5H-0.2L-0.2A	279	15.1	65	35
Tailored 0.6H-0.2L-0.2A	279	15.3	65	35
Tailored 0.7H-0.2L-0.2A	279	15.4	65	35
Tailored 0.8H-0.2L-0.2A	279	15.6	65	35
Tailored 0.9H-0.2L-0.2A	279	15.8	65	35
Tailored 0.1H-0.3L-0.2A	311	13.5	86	42
Tailored 0.2H-0.3L-0.2A	316	16.8	87	44
Tailored 0.3H-0.3L-0.2A	317	18.3	88	44
Tailored 0.4H-0.3L-0.2A	317	19.1	88	45
Tailored 0.5H-0.3L-0.2A	318	19.6	88	45
Tailored 0.6H-0.3L-0.2A	318	19.8	88	45
Tailored 0.7H-0.3L-0.2A	318	19.9	88	45
Tailored 0.8H-0.3L-0.2A	318	20.1	88	45
Tailored 0.9H-0.3L-0.2A	318	20.3	88	45
Tailored 0.1H-0.4L-0.2A	330	14.7	98	46
Tailored 0.2H-0.4L-0.2A	335	18.6	101	48
Tailored 0.3H-0.4L-0.2A	336	20.3	101	49
Tailored 0.4H-0.4L-0.2A	337	21.3	101	49
Tailored 0.5H-0.4L-0.2A	337	21.7	102	49
Tailored 0.6H-0.4L-0.2A	337	22.0	102	49
Tailored 0.7H-0.4L-0.2A	337	22.1	102	49
Tailored 0.8H-0.4L-0.2A	337	22.3	102	49
Tailored 0.9H-0.4L-0.2A	337	22.5	102	49
Tailored 0.1H-0.5L-0.2A	338	15.3	105	48
Tailored 0.2H-0.5L-0.2A	344	19.5	108	50
Tailored 0.3H-0.5L-0.2A	346	21.3	108	51
Tailored 0.4H-0.5L-0.2A	346	22.3	109	51
Tailored 0.5H-0.5L-0.2A	346	22.8	109	51
Tailored 0.6H-0.5L-0.2A	346	23.0	109	51
Tailored 0.7H-0.5L-0.2A	346	23.2	109	51
Tailored 0.8H-0.5L-0.2A	346	23.3	109	51
Tailored 0.9H-0.5L-0.2A	346	23.5	109	51
Tailored 0.1H-0.6L-0.2A	342	15.7	108	49
Tailored 0.2H-0.6L-0.2A	348	19.9	111	51
Tailored 0.3H-0.6L-0.2A	350	21.8	112	51
Tailored 0.4H-0.6L-0.2A	350	22.8	112	52
Tailored 0.5H-0.6L-0.2A	350	23.3	112	52
Tailored 0.6H-0.6L-0.2A	351	23.5	112	52
Tailored 0.7H-0.6L-0.2A	351	23.7	112	52
Tailored 0.8H-0.6L-0.2A	351	23.8	112	52
Tailored 0.9H-0.6L-0.2A	351	24.0	112	52
Tailored 0.1H-0.7L-0.2A	343	15.8	109	49
Tailored 0.2H-0.7L-0.2A	349	20.1	112	51
Tailored 0.3H-0.7L-0.2A	351	22.0	113	52
Tailored 0.4H-0.7L-0.2A	351	23.0	113	52
Tailored 0.5H-0.7L-0.2A	352	23.5	113	52
Tailored 0.6H-0.7L-0.2A	352	23.7	113	52
Tailored 0.7H-0.7L-0.2A	352	23.8	113	52
Tailored 0.8H-0.7L-0.2A	352	24.0	113	52
Tailored 0.9H-0.7L-0.2A	352	24.2	113	52
Tailored 0.1H-0.8L-0.2A	343	15.8	109	49
Tailored 0.2H-0.8L-0.2A	350	20.1	112	51
Tailored 0.3H-0.8L-0.2A	351	22.0	113	52
Tailored 0.4H-0.8L-0.2A	352	23.0	113	52
Tailored 0.5H-0.8L-0.2A	352	23.5	113	52
Tailored 0.6H-0.8L-0.2A	352	23.7	113	52
Tailored 0.7H-0.8L-0.2A	352	23.9	113	52
Tailored 0.8H-0.8L-0.2A	352	24.0	113	52
Tailored 0.9H-0.8L-0.2A	352	24.2	113	52
Tailored 0.1H-0.9L-0.2A	343	15.8	109	49
Tailored 0.2H-0.9L-0.2A	350	20.1	112	51
Tailored 0.3H-0.9L-0.2A	351	22.0	113	52
Tailored 0.4H-0.9L-0.2A	352	23.0	113	52
Tailored 0.5H-0.9L-0.2A	352	23.5	113	52
Tailored 0.6H-0.9L-0.2A	352	23.7	113	52
Tailored 0.7H-0.9L-0.2A	352	23.9	113	52
Tailored 0.8H-0.9L-0.2A	352	24.0	113	52
Tailored 0.9H-0.9L-0.2A	352	24.2	113	52
Tailored 0.1H-0.3L-0.3A	324	15.3	89	51
Tailored 0.2H-0.3L-0.3A	330	19.8	92	54
Tailored 0.3H-0.3L-0.3A	332	22.2	92	55
Tailored 0.4H-0.3L-0.3A	333	23.5	92	55
Tailored 0.5H-0.3L-0.3A	333	24.2	93	55
Tailored 0.6H-0.3L-0.3A	333	24.5	93	55
Tailored 0.7H-0.3L-0.3A	333	24.7	93	55
Tailored 0.8H-0.3L-0.3A	333	24.8	93	55
Tailored 0.9H-0.3L-0.3A	333	25.0	93	55
Tailored 0.1H-0.4L-0.3A	346	17.0	103	57
Tailored 0.2H-0.4L-0.3A	354	22.5	107	60
Tailored 0.3H-0.4L-0.3A	356	25.3	107	61
Tailored 0.4H-0.4L-0.3A	356	26.9	108	62
Tailored 0.5H-0.4L-0.3A	357	27.6	108	62
Tailored 0.6H-0.4L-0.3A	357	28.0	108	62
Tailored 0.7H-0.4L-0.3A	357	28.1	108	62
Tailored 0.8H-0.4L-0.3A	357	28.3	108	62
Tailored 0.9H-0.4L-0.3A	357	28.5	108	62
Tailored 0.1H-0.5L-0.3A	356	17.8	111	60
Tailored 0.2H-0.5L-0.3A	365	23.8	115	63
Tailored 0.3H-0.5L-0.3A	367	26.9	116	64
Tailored 0.4H-0.5L-0.3A	368	28.6	116	65
Tailored 0.5H-0.5L-0.3A	368	29.3	116	65
Tailored 0.6H-0.5L-0.3A	368	29.6	116	65
Tailored 0.7H-0.5L-0.3A	368	29.8	116	65
Tailored 0.8H-0.5L-0.3A	368	30.0	116	65
Tailored 0.9H-0.5L-0.3A	368	30.2	116	65
Tailored 0.1H-0.6L-0.3A	361	18.3	114	61
Tailored 0.2H-0.6L-0.3A	370	24.5	118	64
Tailored 0.3H-0.6L-0.3A	372	27.6	119	65
Tailored 0.4H-0.6L-0.3A	373	29.3	120	66
Tailored 0.5H-0.6L-0.3A	373	30.1	120	66
Tailored 0.6H-0.6L-0.3A	373	30.4	120	66
Tailored 0.7H-0.6L-0.3A	373	30.6	120	66
Tailored 0.8H-0.6L-0.3A	373	30.7	120	66
Tailored 0.9H-0.6L-0.3A	373	30.9	120	66
Tailored 0.1H-0.7L-0.3A	362	18.5	115	61
Tailored 0.2H-0.7L-0.3A	371	24.7	120	65
Tailored 0.3H-0.7L-0.3A	373	27.8	121	66
Tailored 0.4H-0.7L-0.3A	374	29.6	121	66
Tailored 0.5H-0.7L-0.3A	374	30.3	121	66
Tailored 0.6H-0.7L-0.3A	375	30.6	121	66
Tailored 0.7H-0.7L-0.3A	375	30.8	121	66
Tailored 0.8H-0.7L-0.3A	375	31.0	121	66
Tailored 0.9H-0.7L-0.3A	375	31.2	121	66
Tailored 0.1H-0.8L-0.3A	362	18.5	115	61
Tailored 0.2H-0.8L-0.3A	371	24.7	120	65
Tailored 0.3H-0.8L-0.3A	374	27.9	121	66
Tailored 0.4H-0.8L-0.3A	374	29.6	121	66
Tailored 0.5H-0.8L-0.3A	375	30.3	121	66
Tailored 0.6H-0.8L-0.3A	375	30.6	121	66
Tailored 0.7H-0.8L-0.3A	375	30.8	121	66
Tailored 0.8H-0.8L-0.3A	375	31.0	121	66
Tailored 0.9H-0.8L-0.3A	375	31.2	121	66
Tailored 0.1H-0.9L-0.3A	362	18.5	115	61
Tailored 0.2H-0.9L-0.3A	371	24.7	120	65
Tailored 0.3H-0.9L-0.3A	374	27.9	121	66
Tailored 0.4H-0.9L-0.3A	374	29.6	121	66
Tailored 0.5H-0.9L-0.3A	375	30.3	121	66
Tailored 0.6H-0.9L-0.3A	375	30.6	121	66
Tailored 0.7H-0.9L-0.3A	375	30.8	121	66
Tailored 0.8H-0.9L-0.3A	375	31.0	121	66
Tailored 0.9H-0.9L-0.3A	375	31.2	121	66
Tailored 0.1H-0.4L-0.4A	355	18.2	105	64
Tailored 0.2H-0.4L-0.4A	365	25.0	109	69
Tailored 0.3H-0.4L-0.4A	367	28.5	110	71
Tailored 0.4H-0.4L-0.4A	368	30.4	110	71
Tailored 0.5H-0.4L-0.4A	368	31.3	110	71
Tailored 0.6H-0.4L-0.4A	368	31.6	110	71
Tailored 0.7H-0.4L-0.4A	368	31.8	110	71
Tailored 0.8H-0.4L-0.4A	369	32.0	110	71
Tailored 0.9H-0.4L-0.4A	369	32.2	111	71
Tailored 0.1H-0.5L-0.4A	366	19.2	113	68
Tailored 0.2H-0.5L-0.4A	377	26.6	118	73
Tailored 0.3H-0.5L-0.4A	380	30.4	119	74
Tailored 0.4H-0.5L-0.4A	380	32.5	119	75
Tailored 0.5H-0.5L-0.4A	381	33.4	119	75
Tailored 0.6H-0.5L-0.4A	381	33.7	119	75
Tailored 0.7H-0.5L-0.4A	381	33.9	119	75
Tailored 0.8H-0.5L-0.4A	381	34.1	119	75
Tailored 0.9H-0.5L-0.4A	381	34.3	119	75
Tailored 0.1H-0.6L-0.4A	371	19.7	117	69
Tailored 0.2H-0.6L-0.4A	382	27.3	121	74
Tailored 0.3H-0.6L-0.4A	385	31.3	122	76
Tailored 0.4H-0.6L-0.4A	386	33.3	123	76
Tailored 0.5H-0.6L-0.4A	386	34.2	123	76
Tailored 0.6H-0.6L-0.4A	386	34.5	123	76
Tailored 0.7H-0.6L-0.4A	386	34.7	123	76
Tailored 0.8H-0.6L-0.4A	386	34.9	123	76
Tailored 0.9H-0.6L-0.4A	386	35.1	123	76
Tailored 0.1H-0.7L-0.4A	372	19.8	118	69
Tailored 0.2H-0.7L-0.4A	384	27.5	122	75
Tailored 0.3H-0.7L-0.4A	386	31.5	123	76
Tailored 0.4H-0.7L-0.4A	387	33.5	124	76
Tailored 0.5H-0.7L-0.4A	387	34.4	124	77
Tailored 0.6H-0.7L-0.4A	387	34.8	124	77
Tailored 0.7H-0.7L-0.4A	388	35.0	124	77
Tailored 0.8H-0.7L-0.4A	388	35.1	124	77
Tailored 0.9H-0.7L-0.4A	388	35.3	124	77
Tailored 0.1H-0.8L-0.4A	372	19.9	118	69
Tailored 0.2H-0.8L-0.4A	384	27.6	123	75
Tailored 0.3H-0.8L-0.4A	386	31.5	124	76
Tailored 0.4H-0.8L-0.4A	387	33.5	124	76
Tailored 0.5H-0.8L-0.4A	388	34.4	124	77
Tailored 0.6H-0.8L-0.4A	388	34.8	124	77
Tailored 0.7H-0.8L-0.4A	388	35.0	124	77
Tailored 0.8H-0.8L-0.4A	388	35.1	124	77
Tailored 0.9H-0.8L-0.4A	388	35.3	124	77
Tailored 0.1H-0.9L-0.4A	372	19.9	118	69
Tailored 0.2H-0.9L-0.4A	384	27.6	123	75
Tailored 0.3H-0.9L-0.4A	386	31.5	124	76
Tailored 0.4H-0.9L-0.4A	387	33.5	124	76
Tailored 0.5H-0.9L-0.4A	388	34.4	124	77
Tailored 0.6H-0.9L-0.4A	388	34.8	124	77
Tailored 0.7H-0.9L-0.4A	388	35.0	124	77
Tailored 0.8H-0.9L-0.4A	388	35.1	124	77
Tailored 0.9H-0.9L-0.4A	388	35.3	124	77
Tailored 0.1H-0.5L-0.5A	373	20.2	114	73
Tailored 0.2H-0.5L-0.5A	385	28.7	119	80
Tailored 0.3H-0.5L-0.5A	388	33.4	120	82
Tailored 0.4H-0.5L-0.5A	389	35.7	120	82
Tailored 0.5H-0.5L-0.5A	389	36.6	120	82
Tailored 0.6H-0.5L-0.5A	389	37.0	120	83
Tailored 0.7H-0.5L-0.5A	389	37.2	120	83
Tailored 0.8H-0.5L-0.5A	389	37.4	120	83
Tailored 0.9H-0.5L-0.5A	389	37.6	120	83
Tailored 0.1H-0.6L-0.5A	377	20.7	118	74
Tailored 0.2H-0.6L-0.5A	390	29.5	123	81
Tailored 0.3H-0.6L-0.5A	393	34.2	124	83
Tailored 0.4H-0.6L-0.5A	394	36.5	124	84
Tailored 0.5H-0.6L-0.5A	394	37.5	124	84
Tailored 0.6H-0.6L-0.5A	394	37.9	124	84
Tailored 0.7H-0.6L-0.5A	395	38.1	124	84
Tailored 0.8H-0.6L-0.5A	395	38.2	124	84
Tailored 0.9H-0.6L-0.5A	395	38.4	124	84
Tailored 0.1H-0.7L-0.5A	378	20.8	119	75
Tailored 0.2H-0.7L-0.5A	392	29.7	124	82
Tailored 0.3H-0.7L-0.5A	395	34.5	125	83
Tailored 0.4H-0.7L-0.5A	396	36.8	125	84
Tailored 0.5H-0.7L-0.5A	396	37.7	125	84
Tailored 0.6H-0.7L-0.5A	396	38.1	125	84
Tailored 0.7H-0.7L-0.5A	396	38.3	125	84
Tailored 0.8H-0.7L-0.5A	396	38.5	125	84
Tailored 0.9H-0.7L-0.5A	396	38.7	125	84
Tailored 0.1H-0.8L-0.5A	379	20.9	119	75
Tailored 0.2H-0.8L-0.5A	392	29.7	124	82
Tailored 0.3H-0.8L-0.5A	395	34.5	125	83
Tailored 0.4H-0.8L-0.5A	396	36.8	125	84
Tailored 0.5H-0.8L-0.5A	396	37.8	125	84
Tailored 0.6H-0.8L-0.5A	396	38.1	125	84
Tailored 0.7H-0.8L-0.5A	396	38.3	125	84
Tailored 0.8H-0.8L-0.5A	396	38.5	125	84
Tailored 0.9H-0.8L-0.5A	396	38.7	125	84
Tailored 0.1H-0.9L-0.5A	379	20.9	119	75
Tailored 0.2H-0.9L-0.5A	392	29.7	124	82
Tailored 0.3H-0.9L-0.5A	395	34.5	125	83
Tailored 0.4H-0.9L-0.5A	396	36.8	125	84
Tailored 0.5H-0.9L-0.5A	396	37.8	125	84
Tailored 0.6H-0.9L-0.5A	396	38.1	125	84
Tailored 0.7H-0.9L-0.5A	396	38.3	125	84
Tailored 0.8H-0.9L-0.5A	396	38.5	125	84
Tailored 0.9H-0.9L-0.5A	396	38.7	125	84
Tailored 0.1H-0.6L-0.6A	381	21.5	118	78
Tailored 0.2H-0.6L-0.6A	395	31.2	123	86
Tailored 0.3H-0.6L-0.6A	399	36.4	124	88
Tailored 0.4H-0.6L-0.6A	400	39.0	125	89
Tailored 0.5H-0.6L-0.6A	400	40.0	125	89
Tailored 0.6H-0.6L-0.6A	400	40.3	125	89
Tailored 0.7H-0.6L-0.6A	400	40.6	125	89
Tailored 0.8H-0.6L-0.6A	400	40.7	125	89
Tailored 0.9H-0.6L-0.6A	400	40.9	125	89
Tailored 0.1H-0.7L-0.6A	383	21.6	119	79
Tailored 0.2H-0.7L-0.6A	397	31.4	124	87
Tailored 0.3H-0.7L-0.6A	400	36.6	125	89
Tailored 0.4H-0.7L-0.6A	401	39.2	126	89
Tailored 0.5H-0.7L-0.6A	401	40.2	126	89
Tailored 0.6H-0.7L-0.6A	401	40.6	126	89
Tailored 0.7H-0.7L-0.6A	402	40.8	126	89
Tailored 0.8H-0.7L-0.6A	402	41.0	126	89
Tailored 0.9H-0.7L-0.6A	402	41.2	126	89
Tailored 0.1H-0.8L-0.6A	383	21.6	119	79
Tailored 0.2H-0.8L-0.6A	397	31.4	124	87
Tailored 0.3H-0.8L-0.6A	400	36.7	126	89
Tailored 0.4H-0.8L-0.6A	401	39.2	126	89
Tailored 0.5H-0.8L-0.6A	402	40.2	126	89
Tailored 0.6H-0.8L-0.6A	402	40.6	126	89
Tailored 0.7H-0.8L-0.6A	402	40.8	126	89
Tailored 0.8H-0.8L-0.6A	402	41.0	126	90
Tailored 0.9H-0.8L-0.6A	402	41.2	126	90
Tailored 0.1H-0.9L-0.6A	383	21.6	119	79
Tailored 0.2H-0.9L-0.6A	397	31.4	124	87
Tailored 0.3H-0.9L-0.6A	400	36.7	126	89
Tailored 0.4H-0.9L-0.6A	401	39.2	126	89
Tailored 0.5H-0.9L-0.6A	402	40.2	126	89
Tailored 0.6H-0.9L-0.6A	402	40.6	126	89
Tailored 0.7H-0.9L-0.6A	402	40.8	126	89
Tailored 0.8H-0.9L-0.6A	402	41.0	126	90
Tailored 0.9H-0.9L-0.6A	402	41.2	126	90
Tailored 0.1H-0.7L-0.7A	385	22.1	119	81
Tailored 0.2H-0.7L-0.7A	400	32.5	124	90
Tailored 0.3H-0.7L-0.7A	404	38.0	126	92
Tailored 0.4H-0.7L-0.7A	405	40.6	126	93
Tailored 0.5H-0.7L-0.7A	405	41.7	126	93
Tailored 0.6H-0.7L-0.7A	405	42.0	126	93
Tailored 0.7H-0.7L-0.7A	405	42.3	126	93
Tailored 0.8H-0.7L-0.7A	405	42.4	126	93
Tailored 0.9H-0.7L-0.7A	405	42.6	126	93
Tailored 0.1H-0.8L-0.7A	386	22.1	119	81
Tailored 0.2H-0.8L-0.7A	401	32.5	125	90
Tailored 0.3H-0.8L-0.7A	404	38.0	126	92
Tailored 0.4H-0.8L-0.7A	405	40.7	126	93
Tailored 0.5H-0.8L-0.7A	405	41.7	126	93
Tailored 0.6H-0.8L-0.7A	405	42.1	126	93
Tailored 0.7H-0.8L-0.7A	406	42.3	126	93
Tailored 0.8H-0.8L-0.7A	406	42.4	126	93
Tailored 0.9H-0.8L-0.7A	406	42.6	126	93
Tailored 0.1H-0.9L-0.7A	386	22.1	119	81
Tailored 0.2H-0.9L-0.7A	401	32.5	125	90
Tailored 0.3H-0.9L-0.7A	404	38.0	126	92
Tailored 0.4H-0.9L-0.7A	405	40.7	126	93
Tailored 0.5H-0.9L-0.7A	405	41.7	126	93
Tailored 0.6H-0.9L-0.7A	405	42.1	126	93
Tailored 0.7H-0.9L-0.7A	406	42.3	126	93
Tailored 0.8H-0.9L-0.7A	406	42.4	126	93
Tailored 0.9H-0.9L-0.7A	406	42.6	126	93
Tailored 0.1H-0.8L-0.8A	387	22.5	119	83
Tailored 0.2H-0.8L-0.8A	403	33.3	125	92
Tailored 0.3H-0.8L-0.8A	406	38.9	126	94
Tailored 0.4H-0.8L-0.8A	407	41.5	126	95
Tailored 0.5H-0.8L-0.8A	407	42.5	126	95
Tailored 0.6H-0.8L-0.8A	407	42.9	126	95
Tailored 0.7H-0.8L-0.8A	408	43.1	126	95
Tailored 0.8H-0.8L-0.8A	408	43.3	126	95
Tailored 0.9H-0.8L-0.8A	408	43.5	126	95
Tailored 0.1H-0.9L-0.8A	387	22.5	119	83
Tailored 0.2H-0.9L-0.8A	403	33.3	125	92
Tailored 0.3H-0.9L-0.8A	406	38.9	126	94
Tailored 0.4H-0.9L-0.8A	407	41.5	126	95
Tailored 0.5H-0.9L-0.8A	407	42.5	126	95
Tailored 0.6H-0.9L-0.8A	407	42.9	126	95
Tailored 0.7H-0.9L-0.8A	408	43.1	126	95
Tailored 0.8H-0.9L-0.8A	408	43.3	126	95
Tailored 0.9H-0.9L-0.8A	408	43.5	126	95
Tailored 0.1H-0.9L-0.9A	388	22.6	119	84
Tailored 0.2H-0.9L-0.9A	403	33.4	125	93
Tailored 0.3H-0.9L-0.9A	407	39.0	126	95
Tailored 0.4H-0.9L-0.9A	408	41.6	126	95
Tailored 0.5H-0.9L-0.9A	408	42.7	126	96
Tailored 0.6H-0.9L-0.9A	408	43.0	126	96
Tailored 0.7H-0.9L-0.9A	408	43.3	126	96
Tailored 0.8H-0.9L-0.9A	408	43.4	126	96
Tailored 0.9H-0.9L-0.9A	408	43.6	126	96
1Policies used in Canada, Australia, and the UK. Minimum interval in days for women (W) and for men (W) are indicated.
2Three example tailored policies. Maximum allowable risks for hemoglobin defferal (H), low iron donation (L), and absent iron donation (A) are indicated.