Notes of Analysis of Functional MRI
1
Overview
2
Principles of BOLD fMRI
2.1
神經活動的生理學
2.1.1
膜電位
2.1.2
離子通道與幫浦
2.1.3
動作電位
2.1.4
突觸
2.1.5
放訊的能量限制
2.1.6
Neurovascular Coupling
2.1.7
CBF and
\(\sf{O_2}\)
Consumption Mismatch
2.1.8
Coupling Properties
2.1.9
Alteration Factors
2.2
fMRI 的原理
2.2.1
fMRI BOLD signal
2.2.2
Biomarkers of brain activation
2.2.3
常見的 fMRI protocol
3
Experimental Design of BOLD fMRI
3.1
實驗設計的類型
3.1.1
Simple Subtraction
3.1.2
Categorical Design
3.1.3
Factorial Design
3.1.4
Parametric Design
3.2
刺激時點設計
3.2.1
Block Design
3.2.2
Event‐Related (ER) Designs
3.3
總結：Rules of thumb
呈現刺激的方法
BOLD 與 HRF 的特性
4
Neuroanatomy and Image Atlas
4.1
Lobes of the Cerebral Cortex
4.1.1
Telencephalon 端腦
4.1.2
Frontal Lobe
4.1.3
Parietal Lobe
4.1.4
Temporal Lobe
4.1.5
Occipital Lobe
4.1.6
Insular Lobe
4.1.7
Vasculature of cerebrum and MR Angiography
4.2
White Matter of the Cerebral Hemisphere
4.3
Image Atlas
5
Image Preprocessing of fMRI
5.1
先備知識
5.1.1
相關軟體
5.1.2
常見的 fMRI protocol
5.1.3
DICOM (1993) 與 DICOM format
5.2
資料前處理
5.2.1
前處理程序
5.2.2
匯入 DICOM
5.2.3
Batch of SPM fMRI preprocessing
5.2.4
Correction for slice timing
5.2.5
Realignment of head motion
5.2.6
Co‐registration
5.2.7
Spatial normalization
5.2.8
Gaussian spatial smoothing
5.2.9
Tissue segmentation
5.2.10
Check the Data
5.3
Parameter Setup of SPM Batch
5.3.1
Correction for Slice Timing
5.3.2
Realignment of head motion
5.3.3
Co‐registration
5.3.4
Spatial normalization
5.3.5
Gaussian spatial smoothing
5.3.6
Tissue segmentation
6
Brain Activation: General Linear Model
6.1
先備知識
6.1.1
相關軟體
6.2
General Linear Model
6.2.1
N‐Back fMRI Data Acquisition
6.2.2
GLM 模型
6.2.3
參數估計
6.2.4
Specify 1st‐level Model
6.2.5
Statistical Analysis: Design
6.2.6
Estimate Model
6.2.7
Review Results
6.2.8
xjview
6.3
SPM Subject Analysis: 1st‐level
6.4
SPM Group Analysis: 2nd‐level
7
Resting-State Brain Activity: ReHo and ALFF
8
Brain Network: Independent Component Analysis
9
Brain Network: Functional Connectivity
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Notes of
Analysis of Functional MRI
7
Resting-State Brain Activity: ReHo and ALFF