Chapter 9 Previous line

Previous line identifier is [pl]

9.1 Definition

Instrument previous line refers to any anticancer treatment received, either for a prior cancer or for the current cancer, before the current line.

The current line is the most recently administered one that contains immune checkpoint inhibitors. It can be ongoing at the time of index cardiotoxicity, or may have been interrupted.

9.2 Abbreviations

Here is a list of abbreviations used in several variables in the demo instrument.

Abbreviation(s) Feature

atez

avel

cemi

durv

nivo

ipil

pemb

trem

Standardized 4-character abbreviations of immune checkpoint inhibitors

Atezolizumab, avelumab, cemiplimab, durvalumab, nivolumab, ipilimumab, pembrolizumab, tremelimumab

pd1

pdl1

ctla4

When drug name is not know, standardized abbreviations related to ICI class.

Anti-PD1, anti-PD-L1, anti-CTLA4

Also pd1_other, pdl1_other, and ctla4_other to refer to an ICI from a class that is not in the aforementioned list (e.g. a new anti-PD1)