Chapter 6 Index cardiotoxicity
Index cardiotoxicity identifier is [ic]
There is a little ambiguity here: index cardiotoxicity refers both to the date of cardiotoxicity diagnosis AND date of hospital admission (if any) for this cardiotoxicity.
6.1 Abbreviations
| Abbreviation(s) | Feature |
|---|---|
| Clinical work-up | |
sy |
Symptoms |
ctx |
Cardiotoxicity (used for the description of timings between a ctx symptoms ctx sy and index date, and grading). |
pe |
Physical examination features |
irae |
Features of non-cardiac immune related adverse events at the index date |
hyper, hypo, aiha, attp, hus, aa, id, bd, scar |
For iraes subclasses, small adds to refer to the correct subclass (hyperthyroidism, hypothyroidism, auto-immune hemolytic anemia, acquired thrombotic thrombocytopenic purpura, hemolytic and uremic syndrome, aplastic anemia, inflammatory dermatitis, bullous dermatosis, severe cutaneous adverse reaction) |
| Exams | |
bx |
Biopsy features (muscular, cardiac, other) |
lhc |
Left Heart Catheterization |
Treatment section
|
|
| immsup | Immunosuppressant |
| 4-character abbreviation for immunosuppressants | |
|
Intravenous Immunoglobulin Plasmapheresis (PLEX) Tacrolimus or cyclosporin Mycophenolate mofetil Other immunosuppressant ATG / thymoglobulin Infliximab or other anti-TNFalpha Abatacept or belatacept mTOR inhibitors (temsirolimus, everolimus, sirolimus) Cyclophosphamide Azathioprine Rituximab |
ms |
Mechanical support |
aa |
Anti-arrhythmic drugs or devices |
6.2 Biological features
Most normal values of biological parameters are different from one lab to another. Also, users may report bio vars according to different scales.
Examples: troponin upper limit of normal may range from ~ 0.01 to ~ 50. Complete blood count can be reported in G/L or 10^-3/µL (even if the var field asked for reporting with one of them).
It is advised to express biological parameters according to their normal value range if known, or to contrast them into ratios that get rid of the unit (example: neutrophil to lymphocyte ratio)