Table 1
|
|
0
|
1
|
p
|
Missing
|
|
n
|
8346
|
638
|
|
|
|
Male = 1 (%)
|
4366 ( 52.3)
|
440 ( 69.0)
|
<0.001
|
0.0
|
|
Age (median [IQR])
|
79.00 [70.00, 86.00]
|
79.00 [70.00, 84.00]
|
0.518
|
0.0
|
|
AFIB_Combined = 1 (%)
|
2449 ( 29.3)
|
135 ( 21.2)
|
<0.001
|
0.0
|
|
CHF = 1 (%)
|
1279 ( 15.3)
|
106 ( 16.6)
|
0.416
|
0.0
|
|
DM = 1 (%)
|
3269 ( 39.2)
|
334 ( 52.4)
|
<0.001
|
0.0
|
|
Stroke = 1 (%)
|
730 ( 8.7)
|
94 ( 14.7)
|
<0.001
|
0.0
|
|
HTN = 1 (%)
|
6751 ( 80.9)
|
582 ( 91.2)
|
<0.001
|
0.0
|
|
COPD = 1 (%)
|
678 ( 8.1)
|
90 ( 14.1)
|
<0.001
|
0.0
|
|
RenalDysfunction = 1 (%)
|
1407 ( 16.9)
|
219 ( 34.3)
|
<0.001
|
0.0
|
|
IHD = 1 (%)
|
3332 ( 39.9)
|
452 ( 70.8)
|
<0.001
|
0.0
|
|
Pre_Admin_CABG = 1 (%)
|
114 ( 1.4)
|
24 ( 3.8)
|
<0.001
|
0.0
|
|
smoking = 1 (%)
|
1795 ( 21.6)
|
238 ( 37.3)
|
<0.001
|
0.2
|
|
BMI_New (median [IQR])
|
27.55 [24.34, 31.79]
|
27.12 [24.04, 31.22]
|
0.015
|
19.0
|
|
systolicBP_New (median [IQR])
|
133.22 [119.00, 148.00]
|
134.60 [121.53, 150.00]
|
0.005
|
0.0
|
|
post_Index_Rehab_Over2visit = 1 (%)
|
1514 ( 49.5)
|
142 ( 52.2)
|
0.427
|
62.9
|
|
rehabClinicVisits (median [IQR])
|
4.00 [2.00, 10.00]
|
2.00 [1.00, 6.25]
|
0.006
|
89.2
|
|
CR_max (median [IQR])
|
1.30 [1.00, 1.76]
|
1.54 [1.17, 2.20]
|
<0.001
|
4.5
|
|
HGB_min (median [IQR])
|
10.88 [9.43, 12.26]
|
10.41 [8.96, 11.83]
|
<0.001
|
0.3
|
|
Sodium_max (median [IQR])
|
140.00 [138.00, 142.00]
|
140.00 [138.00, 142.00]
|
0.996
|
0.3
|
|
Diuretics_C = 1 (%)
|
5924 ( 71.0)
|
496 ( 77.7)
|
<0.001
|
0.0
|
|
BetaBlockers_C = 1 (%)
|
5995 ( 71.8)
|
520 ( 81.5)
|
<0.001
|
0.0
|
|
Diabetic_C = 1 (%)
|
2896 ( 34.7)
|
287 ( 45.0)
|
<0.001
|
0.0
|
|
ACEARB_C = 1 (%)
|
5887 ( 70.5)
|
530 ( 83.1)
|
<0.001
|
0.0
|
|
Aspirin_C = 1 (%)
|
4989 ( 59.8)
|
521 ( 81.7)
|
<0.001
|
0.0
|
|
Clopidogrel_C = 1 (%)
|
1873 ( 22.4)
|
297 ( 46.6)
|
<0.001
|
0.0
|
|
Prasugrel_C = 1 (%)
|
83 ( 1.0)
|
5 ( 0.8)
|
0.755
|
0.0
|
|
Ticagrelor_C = 1 (%)
|
65 ( 0.8)
|
9 ( 1.4)
|
0.140
|
0.0
|
|
Warfarin_C = 1 (%)
|
2196 ( 26.3)
|
150 ( 23.5)
|
0.132
|
0.0
|
|
Apixaban_C = 1 (%)
|
612 ( 7.3)
|
46 ( 7.2)
|
0.971
|
0.0
|
|
Rivaroxaban_C = 1 (%)
|
355 ( 4.3)
|
25 ( 3.9)
|
0.762
|
0.0
|
|
Dabigatran_C = 1 (%)
|
222 ( 2.7)
|
18 ( 2.8)
|
0.907
|
0.0
|
|
Amiodarone_C = 0 (%)
|
8346 (100.0)
|
638 (100.0)
|
NA
|
0.0
|
|
LipidModifying_C = 1 (%)
|
5695 ( 68.2)
|
560 ( 87.8)
|
<0.001
|
0.0
|
|
Jardiance_C = 1 (%)
|
46 ( 0.6)
|
7 ( 1.1)
|
0.142
|
0.0
|
|
Entresto_C = 1 (%)
|
24 ( 0.3)
|
1 ( 0.2)
|
0.830
|
0.0
|
|
Forxiga_C = 1 (%)
|
14 ( 0.2)
|
2 ( 0.3)
|
0.723
|
0.0
|
|
GLP1RA_C = 1 (%)
|
93 ( 1.1)
|
9 ( 1.4)
|
0.626
|
0.0
|
|
RVSP (median [IQR])
|
47.00 [38.00, 57.00]
|
48.00 [38.00, 59.50]
|
0.242
|
47.1
|
|
LVEF (median [IQR])
|
50.00 [30.00, 60.00]
|
42.50 [30.00, 60.00]
|
0.001
|
42.7
|
|
Norton_Overall (median [IQR])
|
18.00 [15.00, 19.00]
|
18.00 [15.00, 19.00]
|
0.349
|
25.1
|
|
htxorlvad = 1 (%)
|
74 ( 0.9)
|
3 ( 0.5)
|
0.380
|
0.0
|
|
timeGroups (%)
|
|
|
0.812
|
0.0
|
|
Early
|
1964 ( 23.5)
|
143 ( 22.4)
|
|
|
|
Late
|
3821 ( 45.8)
|
297 ( 46.6)
|
|
|
|
Mid
|
2561 ( 30.7)
|
198 ( 31.0)
|
|
|
|
ICD = 1 (%)
|
241 ( 2.9)
|
31 ( 4.9)
|
0.007
|
0.0
|
|
Pacemaker = 1 (%)
|
799 ( 9.6)
|
72 ( 11.3)
|
0.181
|
0.0
|
## exp(coef) [confint] p
## PAD 1.32 [1.20, 1.45] <0.001
Survial
|
|
exp(coef) [confint]
|
p
|
|
PAD
|
1.32 [1.20, 1.45]
|
<0.001
|
## exp(coef) [confint] p
## PAD 1.32 [1.17, 1.50] <0.001
Survial
|
|
exp(coef) [confint]
|
p
|
|
PAD
|
1.32 [1.17, 1.50]
|
<0.001
|
Propensity matching
COPD + Norton
## exp(coef) [confint] p
## PAD 1.25 [1.00, 1.57] 0.053
Survial
|
|
exp(coef) [confint]
|
p
|
|
PAD
|
1.25 [1.00, 1.57]
|
0.053
|
## exp(coef) [confint] p
## PAD 1.24 [0.93, 1.66] 0.146
Survial
|
|
exp(coef) [confint]
|
p
|
|
PAD
|
1.24 [0.93, 1.66]
|
0.146
|
no COPD sensitivity analysis
## exp(coef) [confint] p
## PAD 1.37 [1.07, 1.75] 0.012
Survial
|
|
exp(coef) [confint]
|
p
|
|
PAD
|
1.37 [1.07, 1.75]
|
0.012
|
## exp(coef) [confint] p
## PAD 1.41 [1.04, 1.93] 0.029
Survial
|
|
exp(coef) [confint]
|
p
|
|
PAD
|
1.41 [1.04, 1.93]
|
0.029
|
Matching only on norton
## exp(coef) [confint] p
## PAD 1.31 [1.04, 1.65] 0.021
Survial
|
|
exp(coef) [confint]
|
p
|
|
PAD
|
1.31 [1.04, 1.65]
|
0.021
|
## exp(coef) [confint] p
## PAD 1.09 [0.83, 1.45] 0.530
Survial
|
|
exp(coef) [confint]
|
p
|
|
PAD
|
1.09 [0.83, 1.45]
|
0.530
|