Autism Inpatient Collection (AIC) Phenotypic Data Manual
1 Overview
1.0.1 Using this Manual
This manual was created in R using Bookdown. Use the search function at the top left to quickly locate file names, keywords, or variable names across chapters.
1.0.2 Associated Datasets
In addition to phenotypic data, AIC collected physiology data and biosamples (blood, saliva). These data are separately available on SFARI Base:
AIC Biosensor Data (Imbiriba et al., 2023) - SFARI Base ID DS0000084
[GENETIC DATA] - SFARI Base ID [ID]
1.0.3 AIC Phenotypic Data Sample
| Double-confirmed ASD (N=1544) |
Single-confirmed ASD (N=171) |
|
|---|---|---|
| Sex | ||
| Male | 1236 (80.1%) | 140 (81.9%) |
| Female | 308 (19.9%) | 31 (18.1%) |
| Age at Admission | ||
| Mean (SD) | 12.9 (3.60) | 13.0 (3.74) |
| Median [Min, Max] | 13.0 [4.00, 31.0] | 13.4 [4.10, 24.2] |
| Ethnicity | ||
| Not Hispanic/Latino | 1328 (86.0%) | 122 (71.3%) |
| Hispanic/Latino | 96 (6.2%) | 18 (10.5%) |
| Missing | 120 (7.8%) | 31 (18.1%) |
| Race | ||
| American Indian or Alaskan Native | 6 (0.4%) | 1 (0.6%) |
| Asian | 24 (1.6%) | 3 (1.8%) |
| Black or African American | 137 (8.9%) | 21 (12.3%) |
| Multiple | 96 (6.2%) | 10 (5.8%) |
| Native Hawaiian or Other Pacific Islander | 2 (0.1%) | 0 (0%) |
| Other | 18 (1.2%) | 1 (0.6%) |
| White | 1182 (76.6%) | 108 (63.2%) |
| Missing | 79 (5.1%) | 27 (15.8%) |
See Release Notes for an explanation of double- and single-confirmed ASD.
1.0.4 Data Collection Sites
| Site | Location | PI(s) |
|---|---|---|
| Bradley Hospital | East Providence, Rhode Island | |
| Cincinnati Children’s Hospital | Cincinnati, Ohio | |
| Colorado Children’s Hospital | Aurora, Colorado | |
| Sheppard Pratt Health Systems | Baltimore, Maryland | |
| Spring Harbor Hospital | Westbrook, Maine | |
| Western Psychiatric Institute | Pittsburgh, Pennsylvania |
